Merkel Cell Carcinoma Skin Histology. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. The tumour forms sheets, nests and rarely ribbons. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy.
Merkel Cell Carcinoma Skin Histology , Mcc Begins In These Cells.
Pathology Outlines Merkel Cell Carcinoma. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin.
Merkel cell carcinoma skin lesions classically appear blue, purple, or red in color.
Although merkel cell carcinoma has some visual features that are usually present, it does not have a truly distinctive appearance that allows it to be reliably distinguished from less dangerous skin lesions or other skin cancers. The pathogenesis, clinical features, and diagnosis of mcc are discussed here. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. These cells are organized around hair follicles and are believed to act as some type of touch receptors. Merkel cell carcinoma forms on or just beneath the skin. Merkel cell carcinomas are unlike other skin cancers in that they typically don't appear with an alarming asymmetrical shape or pigmented color. Merkel cells, found in the top layer of the skin, are very close to the. Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma, also known as trabecular adenocarcinoma, is related to skin benign neoplasm and eyelid carcinoma. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Although merkel cell carcinoma has some visual features that are usually present, it does not have a truly distinctive appearance that allows it to be reliably distinguished from less dangerous skin lesions or other skin cancers. Gale encyclopedia of cancer dictionary. Rather, they can look innocuous, even like a bug bite. Merkel cell carcinoma (mcc) of the skin is a rare, aggressive, cutaneous malignancy that predominantly affects older adults with light skin types and has a high propensity for recurrence and metastases 1. Know the signs and symptoms of merkel cell carcinoma. Mccs are dermally based tumors composed of small uniform round blue cells arranged in anastomosing cords, bands and clusters. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. Although merkel cell carcinoma can affect any part of the skin, it is most common on skin that has been chronically exposed to sunlight (for example, the face. Primary neuroendocrine (merkel cell) carcinoma of the skin: Learn the basic features of merkel cell carcinoma (primary cutaneous neuroendocrine carcinoma), including my personal approach to using immunohistochemistry. Its incidence rate rises and is currently about.6/100000/year. Description merkel cells are cells that lie in the middle layers of the skin. Source for information on merkel cell carcinoma: Find out how it's tested for, diagnosed, and staged. Merkel cell carcinoma is different from other skin cancers in that it does not have a common identifiable trait across all cases. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients.
Merkel Cell Carcinoma Treatment Pdq Pdq Cancer Information Summaries Ncbi Bookshelf - Learn About Merkel Cell Carcinoma And Find Information On How We Support And Care For People Merkel Cell Carcinoma:
Merkel Cell. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. The tumour forms sheets, nests and rarely ribbons. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells.
Merkel Cell Carcinoma Dermatology Advisor : Merkel Cell Carcinomas Are Unlike Other Skin Cancers In That They Typically Don't Appear With An Alarming Asymmetrical Shape Or Pigmented Color.
B Histology Of Merkel Cell Carcinoma Download Scientific Diagram. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals.
Merkel Cell Carcinoma Metastatic To The Head Of The Pancreas Insight Medical Publishing . Gale encyclopedia of cancer dictionary.
Conference 15 2008 Case 3 20090128. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions.
Squamous Cell Carcinoma Skin Mypathologyreport Ca : Merkel Cell Carcinoma Most Often Develops In Older People.
Merkel Cell Carcinoma Skin Mypathologyreport Ca. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades.
Conference 15 2008 Case 3 20090128 . Merkel Cell Carcinoma Most Often Develops In Older People.
View Of Merkel Cell Carcinoma Masquerading As Cellulitis A Case Report And Review Of The Literature Current Oncology. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. The tumour forms sheets, nests and rarely ribbons. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population.
Merkel Cell Carcinoma Pathology Dermnet Nz . Although Merkel Cell Carcinoma Can Affect Any Part Of The Skin, It Is Most Common On Skin That Has Been Chronically Exposed To Sunlight (For Example, The Face.
Renan R Ribeiro On Twitter Male 74 Skin Nodule In Preauricular Region H E Shows Proliferation Of Epithelioid Cells Arranged In Nests Separated By Thin Fibrovascular Cores Vascular Invasion Salt Pepper Nuclei. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat.
Advances In Merkel Cell Carcinoma From A Pathologist S Perspective Sciencedirect : Merkel Cells, Found In The Top Layer Of The Skin, Are Very Close To The.
Oncolex Utskriftsvennlig Versjon. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. The tumour forms sheets, nests and rarely ribbons. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions.
Merkel Cell Carcinoma Skin Mypathologyreport Ca - Mccs Are Dermally Based Tumors Composed Of Small Uniform Round Blue Cells Arranged In Anastomosing Cords, Bands And Clusters.
Malignant Lesions Of The External Periocular Tissues Tutorial. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy.
Merkel Cell Carcinoma Wikiwand , A Fit 80 Year Old Woman Presents With A Merkel Cell Carcinoma Of The Middle Of The Right Cheek, 8Mm In Maximal Transverse Diameter.
Case Of The Week 304. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions.
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Case Of The Week 304. Get detailed information about the diagnosis and treatment of newly diagnosed merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. It's a type of skin cancer that occurs when cells in the skin, known as merkel cells, grow uncontrollably. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. Merkel cell carcinoma (mcc) is a rare but aggressive neuroendocrine tumour of the skin with high rate of local recurrence and distant metastatic potential leading to poor outcomes. The tumour forms sheets, nests and rarely ribbons. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cells are normally found as innervated clusters of cells around hair follicles in the basal layer of the epidermis. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells.