Merkel Cell Carcinoma Histology. Most caused by merkel cell polyomavirus. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals.
Merkel Cell Carcinoma Histology - 2 Paulson Kg, Park Sy, Et Al.
Merkel Cell Carcinoma Pathology Residency And Fellowship Program Brown University. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Most caused by merkel cell polyomavirus. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). The tumour forms sheets, nests and rarely ribbons. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer.
A rare disease in which cancer cells form in the skin.
Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cell carcinoma (mcc) is also called neuroendocrine carcinoma of the skin. 2 paulson kg, park sy, et al. Merkel cell carcinoma (mcc) is a primary neuroendocrine carcinoma of the skin. Background merkel cell carcinoma (mcc) is an unusual primary neuroendocrine carcinoma of the skin. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Moreover, mcc lacks distinguishing clinical features, and thus by the time the diagnosis is made. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). Merkel cells, found in the top layer of the skin, are very close to the. Cancer records show that doctors diagnosed about 2,000 mccs in the united states during 2018.1. Merkel cell carcinoma (mcc) of the skin is a rare, aggressive, cutaneous malignancy that predominantly affects older adults with light skin types and has a merkel cell carcinoma: Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cell carcinoma (mcc) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma forms on or just beneath the skin. Merkel cell carcinoma is rare, so it is common for many medical professionals to be unsure of where to start. An overview of merkel cells, merkel cell carcinoma, symptoms, and causes. The reported incidence of mcc has more than tripled in the past 20 years1. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. 36 merkel cell carcinoma (mcc) is a cutaneous neuroendocrine malignancy that exhibits clinically aggressive features and is associated with a poor prognosis. Merkel cell carcinoma is different from other skin cancers in that it does not have a common identifiable trait across all cases. The cancer usually presents as a single reddish or purple lump on a part of the skin that is often exposed to. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma (mcc) is a rare type of skin cancer. Current us incidence and projected increases based on changing demographics. Merkel cell carcinoma most often develops in older people. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features.
Cutaneous Squamous Cell Carcinoma Defining The High Risk Variant Actas Dermo Sifiliograficas English Edition . 50% Of Cases Arise On The Face And 40% On The Limbs.
Histology Of Merkel Cell Carcinoma From Patient In Figure 1 Showing The Download Scientific Diagram. The tumour forms sheets, nests and rarely ribbons. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Most caused by merkel cell polyomavirus. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer.
Merkel Cell Carcinoma Skin Histology : Merkel Cells, Found In The Top Layer Of The Skin, Are Very Close To The.
Merkel Cell Carcinoma In A Steer Sciencedirect. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Most caused by merkel cell polyomavirus. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions.
Merkel Cell Carcinoma Of The Tongue Base Luk 2018 Surgical Practice Wiley Online Library : It is rare in blacks and usually occurs in older people (mean age 70).
Frontiers Histogenesis Of Merkel Cell Carcinoma A Comprehensive Review Oncology. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Most caused by merkel cell polyomavirus. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. The tumour forms sheets, nests and rarely ribbons. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells.
Conference 15 2008 Case 3 20090128 : Merkel Cell Carcinoma (Mcc) Is Also Called Neuroendocrine Carcinoma Of The Skin.
Frontiers Histogenesis Of Merkel Cell Carcinoma A Comprehensive Review Oncology. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. The tumour forms sheets, nests and rarely ribbons. Most caused by merkel cell polyomavirus. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat.
Basal Cell Carcinoma Histology Health Pictures Basal Cell Carcinoma Basal Cell Health Pictures : Mcc Is A Fatal Disease, And Patients Have A Poor Chance Of Survival.
Merkel Cell Carcinoma Skin Histology. Most caused by merkel cell polyomavirus. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features.
A Merkel Cell Carcinoma Trabecular Pattern Uniform Proliferation Of Download Scientific Diagram . It Is Rare In Blacks And Usually Occurs In Older People (Mean Age 70).
Researchers Unlock Keys To Staging And Risk Stratification Of Merkel Cell Carcinoma Consult Qd. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Most caused by merkel cell polyomavirus. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. The tumour forms sheets, nests and rarely ribbons.
Merkel Cell Carcinoma Pathology Dermnet Nz , Merkel Cell Carcinoma (Mcc) Of The Skin Is A Rare, Aggressive, Cutaneous Malignancy That Predominantly Affects Older Adults With Light Skin Types And Has A Merkel Cell Carcinoma:
Histopathology Images Of Small Cell Carcinoma By Pathpedia Com Pathology E Atlas. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Most caused by merkel cell polyomavirus. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. The tumour forms sheets, nests and rarely ribbons. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions.
Merkel Cell Carcinoma Wikipedia . Identified Merkel Cell Polyomavirus (Mcpyv) Integration Into The Host Genome As The Main Event.
The Characteristic Histology Of Melanoma Bcc Scc And Some Rare Skin Download Scientific Diagram. The tumour forms sheets, nests and rarely ribbons. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Most caused by merkel cell polyomavirus. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells.
Merkel Cell Carcinoma Skin Histology - Merkel Cell Carcinoma (Mcc) Of The Skin Is A Rare, Aggressive, Cutaneous Malignancy That Predominantly Affects Older Adults With Light Skin Types And Has A Merkel Cell Carcinoma:
Merkel Cell Carcinoma Springerlink. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). The tumour forms sheets, nests and rarely ribbons. The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Most caused by merkel cell polyomavirus. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells.
Histopathology Showing Merkel Cells Arranged In Rosettes With Mitoses Download Scientific Diagram : Merkel Cell Carcinoma, Also Called Neuroendocrine Cancer Of The Skin, Is An Aggressive Type Of Skin Cancer That Affects Only About 400 People In The With Early Detection And Treatment, Merkel Cell Carcinoma Can Be Well Contained And Even Cured.
Macroscopic And Histologic Appearance Of Metastatic Merkel Cell Download Scientific Diagram. Get detailed information about the diagnosis and treatment of newly diagnosed and recurrent merkel cell carcinoma in this summary for clinicians. Diagnosis requires microscopic evaluation as the clinical appearance is nonspecific and can mimic a variety of benign and malignant skin lesions. Merkel cell carcinoma (mcc) is an uncommon and aggressive cutaneous neoplasm that lacks distinguishing clinical features. The tumour is centered in the dermis with frequent involvement of the overlying epidermis (figures 1, 2) and may invade the subcutaneous fat. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer occurring in about 3 people per 1,000,000 members of the population. Merkel cell carcinoma, abbreviated mcc, is an uncommon aggressive form of skin cancer. Most caused by merkel cell polyomavirus. Since the first description of the merkel cell carcinoma by cyril toker in 1972, the number of studies has significantly increased over the last 4 decades. It is also known as cutaneous apudoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin. Merkel cell carcinoma is a neuroendocrine carcinoma composed of densely blue cells. The tumour forms sheets, nests and rarely ribbons. Merkel cell polyomavirus (mcpyv), is integrated in about 90% of merkel cell carcinomas and seems to interfere with tumor suppressor pathways (borchert, j virol 2014). The cell of origin in mcc might be the pro/pre b cell rather than the merkel cell (zur hausen, cancer res 2013). Merkel cell carcinoma is a highly aggressive primary cutaneous neuroendocrine carcinoma primarily affecting elderly and immunosuppressed individuals. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy.